" /> Thiethylperazine Maleate - CISMeF





Preferred Label : Thiethylperazine Maleate;

NCIt synonyms : 10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate; Thiethylperazine;

NCIt definition : The maleate salt form of triethylperazine, a piperazine phenothiazine derivative and a dopamine antagonist used as antiemetic. Thiethylperazine blocks postsynaptic dopamine 2 (D2) receptors in the medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain. Peripherally, thiethylperazine blocks the vagus nerve in the gastrointestinal tract. In addition, this agent also shows antagonistic activities mediated through muscarinic receptors, H1-receptors, and alpha(1)-receptors.;

UNII : RUK64CF26E;

InChIKey : RVBRTNPNFYFDMZ-SPIKMXEPSA-N;

CAS number : 1179-69-7;

Drug name : Torecan; Norzine;

Molecule name : GS-95;

Chemical formula : C22H29N3S2.2C4H4O4;

NSC code : 130044;

ChEBI ID : CHEBI:32216;

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08/05/2025


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