Risperidone - CISMeF

Preferred Label : Risperidone;

NCIt definition : A benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions. In addition, risperidone has low to moderate affinity for histamine H1, 5-HT1A, 5-HT1C, and 5-HT1D receptors, while it has weak affinity for dopamine D1 and haloperidol-sensitive sigma site receptors.;

UNII : L6UH7ZF8HC;

InChIKey : RAPZEAPATHNIPO-UHFFFAOYSA-N;

CAS number : 106266-06-2;

Chemical formula : C23H27FN4O2;

ChEBI ID : CHEBI:8871;

Details

Origin ID

C29416;

UMLS CUI

C0073393;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing risperidone (medicinal product) [SNOMED CT concept]
- Risperidone (substance) [SNOMED CT concept]
- risperiDONE [LOINC component]
- risperidone [ATC Code]
- risperidone [Substance BNPC]
- risperidone [MeSH concept]
- risperidone [MeSH Descriptor]
Validated automatic mappings to BTNT
- risperidone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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