Ramipril - CISMeF

Preferred Label : Ramipril;

NCIt definition : A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de-esterification into its active form ramiprilat, which inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This abolishes the potent vasoconstrictive actions of angiotensin II and leads to vasodilatation. This agent also causes an increase in bradykinin levels and a decrease in angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis.;

UNII : L35JN3I7SJ;

InChIKey : HDACQVRGBOVJII-JBDAPHQKSA-N;

CAS number : 87333-19-5;

Drug name : Altace;

Chemical formula : C23H32N2O5;

ChEBI ID : CHEBI:8774;

Codes from synonyms : 32054;

Details

Origin ID

C29411;

UMLS CUI

C0072973;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing ramipril (medicinal product) [SNOMED CT concept]
- Ramipril [ICD-11 Extension code]
- Ramipril [LOINC component]
- Ramipril (substance) [SNOMED CT concept]
- ramipril [ATC Code]
- ramipril [Substance BNPC]
- ramipril [MeSH concept]
- ramipril [MeSH Descriptor]
Validated automatic mappings to BTNT
- ramipril [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_target
- Angiotensin-Converting Enzyme [NCIt concept]

Keyword's position in hierarchy(ies) :

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