" /> Ramipril - CISMeF





Preferred Label : Ramipril;

NCIt definition : A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de-esterification into its active form ramiprilat, which inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This abolishes the potent vasoconstrictive actions of angiotensin II and leads to vasodilatation. This agent also causes an increase in bradykinin levels and a decrease in angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis.;

UNII : L35JN3I7SJ;

InChIKey : HDACQVRGBOVJII-JBDAPHQKSA-N;

CAS number : 87333-19-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 87333-19-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Altace;

Chemical formula : C23H32N2O5;

ChEBI ID : CHEBI:8774;

Codes from synonyms : 32054;

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16/05/2024


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