Lisinopril - CISMeF

Preferred Label : Lisinopril;

NCIt related terms : Zestril; N2-[(1S)-1-Carboxy-3-phenylpropyl]-L-lysyl-L-proline, Dihydrate; Prinivil;

NCIt definition : An orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Lisinopril, a synthetic peptide derivative, specifically and competitively inhibits ACE, which results in a decrease in the production of the potent vasoconstrictor angiotensin II and, so, diminished vasopressor activity. In addition, angiotensin II-stimulated aldosterone secretion by the adrenal cortex is decreased which results in a decrease in sodium and water retention and an increase in serum potassium.;

Alternative definition : NCI-GLOSS: A drug used to treat high blood pressure and certain heart conditions. It is also being studied in the prevention and treatment of side effects caused by some anticancer drugs. It blocks certain enzymes that cause blood vessels to constrict (narrow). It is a type of angiotensin-converting enzyme (ACE) inhibitor.;

UNII : E7199S1YWR;

InChIKey : CZRQXSDBMCMPNJ-ZUIPZQNBSA-N;

CAS number : 83915-83-7;

Drug name : Prinivil; Zestril;

Chemical formula : C21H31N3O5.2H2O;

ChEBI ID : CHEBI:6503;

Codes from synonyms : 32058; CDR0000662968; CDR0000662967; CDR0000662970;

Details

Origin ID

C29159;

UMLS CUI

C0065374;

Currated CISMeF NLP mapping
- Lisinopril [Substance BNPC]
- Lisinopril [ICD-11 Extension code]
- Lisinopril [LOINC component]
- Lisinopril [ICHI extension code]
- Lisinopril [SMS substance]
- Lisinopril (substance) [SNOMED CT concept]
- lisinopril [MeSH Descriptor]
- lisinopril [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lisinopril [Substance BNPC]
- Lisinopril [ICD-11 Extension code]
- Lisinopril [LOINC component]
- Lisinopril (substance) [SNOMED CT concept]
- Product containing lisinopril (medicinal product) [SNOMED CT concept]
- lisinopril [ATC Code]
- lisinopril [MeSH concept]
- lisinopril [MeSH Descriptor]
Validated automatic mappings to BTNT
- lisinopril [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Angiotensin-Converting Enzyme [NCIt concept]

Keyword's position in hierarchy(ies) :

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