K-RAS ASP-12 Mutant Protein

Preferred Label : K-RAS ASP-12 Mutant Protein;

NCIt definition : A mutant form of the p21-ras protein transcribed from a mutant form of the oncogene K-ras. K-Ras is located in the plasma membrane and transduces growth and differentiation signals from activated receptors to protein kinases within the cell. K-RAS ASP-12 contains a mutation at codon 12 and may be used in cancer immunotherapy. (NCI04);

Details

Origin ID

C29135;

UMLS CUI

C1517632;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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