NCIt definition : A peptide derived from the tumor suppressor protein Von Hippel-Lindau (VHL). This
peptide, sequence: MEAGRPRPCCAR, was constructed based on a frameshift mutation of
one of the VHL gene products; the more abundant protein VHLp18(MEA) (where MEA stands
for three amino acids, Met-Glu-Ala). Vaccination with FrSh61(MEA)VHL33 peptide may
stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this
VHL mutant protein.;