Emofolin Sodium

Preferred Label : Emofolin Sodium;

NCIt synonyms : Methyltetrahydrohomofolate; MeTHHF Disodium; Emfolin Sodium;

NCIt definition : The sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity. Emfolin sodium competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, depletion of nucleotide pools, and inhibition of DNA, RNA and protein synthesis. (NCI04);

CAS number : 52386-42-2;

NSC code : 139490;

Details

Origin ID

C29019;

UMLS CUI

C0098575;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 5-methyltetrahydrohomofolate [MeSH concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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