NCIt definition : The mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing
activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors
in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle
and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia
(BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors
in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent
decrease in peripheral vascular resistance.;
Alternative definition : NCI-GLOSS: A drug used to treat high blood pressure and urinary problems caused by
an enlarged prostate. It relaxes muscle tissue in blood vessels and in the prostate.
Cardura is a type of alpha blocker.;
UNII : 86P6PQK0MU;
CAS number : 77883-43-3;
Drug name : Cardura;
Chemical formula : C23H25N5O5.CH4O3S;
ChEBI ID : CHEBI:4709;
Codes from synonyms : 32047; CDR0000562725; CDR0000543115; CDR0000562552;