Adapalene - CISMeF

Preferred Label : Adapalene;

NCIt synonyms : 6-(4-Methoxy-3-tricyclo(3.3.1.13,7)dec-1-ylphenyl)-2-naphthalenecarboxylic Acid; 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid;

NCIt definition : A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04);

UNII : 1L4806J2QF;

InChIKey : LZCDAPDGXCYOEH-UHFFFAOYSA-N;

CAS number : 106685-40-9;

Drug name : Differin;

Molecule name : CD271;

Chemical formula : C28H28O3;

ChEBI ID : CHEBI:31174;

Codes from synonyms : 30033;

Details

Origin ID

C28989;

UMLS CUI

C0165631;

CISMeF manual mappings
- Adapalene [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Adapalene [MeSH Descriptor]
- Adapalene (substance) [SNOMED CT concept]
- Product containing adapalene (medicinal product) [SNOMED CT concept]
- adapalene [ATC Code]
- adapalene [MeSH concept]
Validated automatic mappings to BTNT
- adapalene [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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