" /> Carvedilol - CISMeF





Preferred Label : Carvedilol;

NCIt related terms : Coreg;

NCIt definition : A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R( ) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to treat high blood pressure and certain heart problems. It is also being studied in the prevention and treatment of side effects caused by some anticancer drugs. Coreg blocks certain receptors on nerve cells and causes blood vessels to dilate (widen). It is a type of antihypertensive agent and a type of antianginal agent.;

UNII : 0K47UL67F2;

InChIKey : OGHNVEJMJSYVRP-UHFFFAOYSA-N;

CAS number : 72956-09-3;

Drug name : Coreg;

Chemical formula : C24H26N2O4;

ChEBI ID : CHEBI:3441;

Codes from synonyms : CDR0000662933; 32052;

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07/05/2025


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