Bupivacaine Hydrochloride

Preferred Label : Bupivacaine Hydrochloride;

NCIt synonyms : Bupivacaine;

NCIt related terms : Sensorcaine; Marcaine;

NCIt definition : A long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.;

Alternative definition : NCI-GLOSS: A drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain following surgery for cancer. It is a type of local anesthetic.;

UNII : 7TQO7W3VT8;

InChIKey : HUCIWBPMHXGLFM-UHFFFAOYSA-N;

CAS number : 73360-54-0;

Drug name : Marcain; Marcaine;

Chemical formula : C18H28N2O.HCl.H2O;

ChEBI ID : CHEBI:60789; CHEBI:31322;

Codes from synonyms : CDR0000597097; CDR0000597096; CDR0000597095;

Details

Origin ID

C28876;

UMLS CUI

C0887621;

Automatic exact mappings (from CISMeF team)
- Bupivacaine [ICHI extension code]
- Product containing bupivacaine (medicinal product) [SNOMED CT concept]
- bupivacaine [MeSH Descriptor]
- bupivacaine [ATC Code]
- bupivacaine [Substance BNPC]
- sensorcaine [MeSH concept]
Currated CISMeF NLP mapping
- Bupivacaine hydrochloride [Substance BNPC]
- Bupivacaine hydrochloride [SMS substance]
- Bupivacaine hydrochloride (substance) [SNOMED CT concept]
- bupivacaine hydrochloride [MeSH concept]
- bupivacaine hydrochloride [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Bupivacaine [LOINC component]
- Bupivacaine [ICD-11 Extension code]
- Bupivacaine [SMS substance]
- Bupivacaine (substance) [SNOMED CT concept]
- bupivacaine [MeSH Descriptor]
- bupivacaine [Substance BNPC]
- bupivacaine [SNOMED Notion]
- bupivacaine [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Bupivacaine [NCIt concept]
is_salt_form_of
- Bupivacaine [NCIt concept]

Keyword's position in hierarchy(ies) :

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