NCIt definition : A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein,
a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted
for an aspartic acid in position 115. It might be used to elicit or boost cellular
immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04);