Preferred Label : Anti-human Chorionic Gonadotropin Vaccine;
NCIt definition : A peptide vaccine consisting of the whole or partial beta subunit of human chorionic
gonadotrophin hormone (hCG), linked to an adjuvant carrier of bacterial or viral origin,
with anti-fertility activity. Anti-human chorionic gonadotropin vaccine blocks the
activity of hCG which is naturally produced by the trophectoderm of the pre-implantation
embryo within a few days of fertilization. hCG is required for the maintenance of
the corpus luteum in the ovary thus ensuring its continued production of progesterone,
which is required for the successful completion of implantation of the blastocyst.
Without progesterone, the corpus luteum regresses, and menstruation is initiated.;
Origin ID : C28719;
UMLS CUI : C0879548;
Semantic type(s)
chemical_or_drug_has_mechanism_of_action
concept_is_in_subset