Verpasep Caltespen

Preferred Label : Verpasep Caltespen;

NCIt synonyms : HPV 16 E7/HSP65 Vaccine; Bovine HSP fusion with E7 of HPV16; HPV E7 Peptide Epitope Vaccine; HspE7; BCG65-E7;

NCIt related terms : HspE7 Therapeutic Vaccine; SGN-00101;

NCIt definition : A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the prevention of cancer. It belongs to the family of drugs called fusion proteins.;

UNII : Z7T0JI2E2I;

CAS number : 295371-00-5;

Molecule name : SGN-00101;

NSC code : 713219;

Codes from synonyms : 20390; NSC0713219; CDR0000306516;

Details

Origin ID

C2811;

UMLS CUI

C1327844;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Protein E7, Human Papillomavirus Type 16 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients