Preferred Label : Proteinase 3:PR1 Peptide;
Obsolete resource : true;
NCIt definition : A synthetic HLA-A2-restricted nonapeptide derived from proteinase 3 with potential
use in cancer immunotherapy. Cytotoxic T lymphocytes (CTL) primed with proteinase
3 PR1 peptide attack leukemic cells that express proteinase 3 aberrantly. Proteinase
3 is a serine proteinase that activates progelatinase A and is involved in metastasis
and angiogenesis. (NCI04);
NCIt note : See 'PR1 Leukemia Peptide Vaccine';
Concept status : Retired_Concept;
Origin ID : C2797;
Semantic type(s)
- has_target
