PR6V10 (ras-12 Asp) Peptide

Preferred Label : PR6V10 (ras-12 Asp) Peptide;

NCIt synonyms : PR6V10 ras-12 Asp Peptide;

NCIt definition : A truncated synthetic form of the oncogene Ras, whose protein product p21 is located in the plasma membrane and transduces growth and differentiation signals from activated receptors to protein kinases within the cell. Because mutated Ras proteins may represent highly specific epitopes for T-cell recognition, PR6V10 (ras-12 Asp) peptide may be used in the vaccine immunotherapy of cancer. (NCI04);

NSC code : 706863;

Details

Origin ID

C2795;

UMLS CUI

C1518811;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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