pNGVL3-hIL12 - CISMeF

Preferred Label : pNGVL3-hIL12;

NCIt synonyms : pNGVL3-hIL12 (IL-12 DNA);

NCIt definition : A plasmid vector encoding interleukin-12 (IL-12) with potential use in the gene therapy of cancer. pNGVL3-hIL12 may induce a high level of IL-12 protein expression during transient transfection of host cells. IL-12 is a proinflammatory cytokine with numerous immunoregulatory functions and may augment host immune responses to tumor cells. (NCI04);

NSC code : 709933;

Details

Origin ID

C2791;

UMLS CUI

C1515683;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Interleukin 12 Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Gene Regulation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Cytokine Receptor Activation [NCIt concept]
- Immunopotentiation [NCIt concept]

Keyword's position in hierarchy(ies) :

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