NCIt definition : A synthetic cancer vaccine derived from a melanoma-associated antigen, MART-1. Antigenic
peptides derived from MART-1 are recognized by CD8 T lymphocytes and have been used
to immunize patients with advanced melanomas; prolonged immunization may result in
a reduction in tumor size. Fowlpox virus is an attractive vector because its genome
is easy to manipulate and it does not multiply in human tissues. (NCI04);