Human gp100 Plasmid DNA Vaccine

Preferred Label : Human gp100 Plasmid DNA Vaccine;

NCIt synonyms : GP100 DNA/VR4951 (Vical); gp100 Plasmid DNA;

NCIt definition : A vaccine consisting of a plasmid DNA encoding the human melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumor cells that express this antigen, resulting in tumor cell lysis. (NCI05);

NSC code : 702980;

Details

Origin ID

C2759;

UMLS CUI

C1515637;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_abnormal_cell
- Melanoma Cell [NCIt concept]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Gene Regulation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- Regulation of Antibody Titer Process [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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