NCIt related terms : Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;
NCIt definition : A spectrum of malignant tumors arising from the soft tissues, characterized morphologically
by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal
tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural
differentiation and the markers that characterize the peripheral primitive neuroectodermal
tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic
abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities.
Pain and the presence of a mass are the most common clinical symptoms.;