Preferred Label : Hereditary Atypical Mole Melanoma Syndrome;
NCIt synonyms : FAMM Syndrome; Familial Atypical Mole Melanoma Syndrome;
NCIt related terms : Familial atypical multiple mole melanoma (FAMMM); familial atypical multiple mole melanoma syndrome; FAMMM syndrome;
CISMeF acronym : FAMM;
NCIt definition : An autosomal dominant hereditary neoplastic syndrome characterized by the presence
of multiple melanocytic nevi, some of which are atypical, and a family history of
melanoma. Patients are at an increased risk of developing melanoma and pancreatic
cancer.;
Alternative definition : NCI-GLOSS: An inherited condition marked by the following: (1) one or more first-
or second-degree relatives (parent, sibling, child, grandparent, grandchild, aunt,
or uncle) with malignant melanoma; (2) many moles, some of which are atypical (asymmetrical,
raised, and/or different shades of tan, brown, black, or red) and often of different
sizes; and (3) moles that have specific features when examined under a microscope.
FAMMM syndrome increases the risk of melanoma and may increase the risk of pancreatic
cancer.;
Neoplastic status : Undetermined;
Codes from synonyms : CDR0000270857; CDR0000270858;
Origin ID : C27264;
UMLS CUI : C2314896;
- Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- disease_has_finding
- disease_has_molecular_abnormality
- disease_mapped_to_gene
- disease_may_have_associated_disease
- pathogenesis_of_disease_involves_gene