NCIt definition : A 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic
activity. Pelitinib irreversibly binds covalently to epidermal growth factor receptors
(EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal transduction
and resulting in apoptosis and suppression of proliferation in tumor cells that overexpress
these receptors.;
Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs
to the family of drugs called epidermal growth factor receptor inhibitors.;
UNII : X5DWL380Z6;
InChIKey : WVUNYSQLFKLYNI-AATRIKPKSA-N;
CAS number : 257933-82-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 257933-82-7
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