" /> Pelitinib - CISMeF





Preferred Label : Pelitinib;

NCIt synonyms : (2E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide;

NCIt related terms : EKB-569;

NCIt definition : A 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity. Pelitinib irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal transduction and resulting in apoptosis and suppression of proliferation in tumor cells that overexpress these receptors.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called epidermal growth factor receptor inhibitors.;

UNII : X5DWL380Z6;

InChIKey : WVUNYSQLFKLYNI-AATRIKPKSA-N;

CAS number : 257933-82-7;

Molecule name : WAY-EKB 569; EKB 569;

Chemical formula : C24H23ClFN5O2;

NSC code : 729742;

ChEBI ID : CHEBI:38927;

Codes from synonyms : 31760; CDR0000390273;

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30/05/2025


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