" /> Zileuton - CISMeF





Preferred Label : Zileuton;

NCIt synonyms : N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea; ( -)-N-Hydroxy-N-(1-benzo[b]thien-2-ylethyl)-urea;

NCIt definition : A synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is used to prevent asthma symptoms and that is being studied in the prevention of lung cancer. It belongs to the family of drugs called leukotriene blockers.;

UNII : V1L22WVE2S;

InChIKey : MWLSOWXNZPKENC-UHFFFAOYSA-N;

CAS number : 111406-87-2;

Drug name : Zyflo;

Chemical formula : C11H12N2O2S;

NSC code : 730712;

ChEBI ID : CHEBI:10112;

Codes from synonyms : CDR0000305998; 20007;

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07/05/2025


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