Iratumumab - CISMeF

Preferred Label : Iratumumab;

NCIt synonyms : Monoclonal Antibody MDX-060; MDX-060 Monoclonal Antibody;

NCIt related terms : MDX-060;

NCIt definition : A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin disease and other lymphomas, and other cancers. (NCI04);

Alternative definition : NCI-GLOSS: A monoclonal antibody that is being studied in the treatment of some lymphomas. Monoclonal antibodies are produced in the laboratory and can locate and bind to cancer cells.;

UNII : AYH22O1B1U;

CAS number : 640735-09-7;

Molecule name : MDX-060;

Codes from synonyms : CDR0000340932;

Details

Origin ID

C26441;

UMLS CUI

C1327954;

Currated CISMeF NLP mapping
- iratumumab [MeSH Supplementary Concept]
- iratumumab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- iratumumab [MeSH Supplementary Concept]
- iratumumab [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Tumor Necrosis Factor Receptor Superfamily Member 8 [NCIt concept]

Keyword's position in hierarchy(ies) :

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