Preferred Label : Ribosome Biogenesis Protein NOP53;
NCIt synonyms : p60; GLTSCR2 Protein; GLTSCR2; GLTSCR2-p60 Protein; PICT-1; Protein Interacting With PTEN Carboxyl Terminus 1; Glioma Tumor Suppressor Candidate Region Gene 2 Protein; Protein Interacting with Carboxyl Terminus 1; Protein Interacting With PTEN C Terminus 1; NOP53;
NCIt definition : Ribosome biogenesis protein NOP53 (478 aa, 54 kDa) is encoded by the human NOP53
gene. This protein plays a role in cellular stress responses, ribosome biogenesis
and the stabilization of the tumor suppressor protein PTEN.;
NCIt note : Glioma tumor suppressor candidate region gene 2 protein interacts with the C-terminal
portion of phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity
protein phosphatase PTEN. This interaction enhances the stability of phosphatidylinositol
3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN. (OMIM);