Telomerase: 540-548 Peptide Vaccine

Preferred Label : Telomerase: 540-548 Peptide Vaccine;

NCIt synonyms : Telomerase:540-548 Peptide; Telomerase 540-548 Peptide Vaccine;

NCIt definition : A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells. (NCI04);

NSC code : 720002;

Details

Origin ID

C2640;

UMLS CUI

C0935896;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Interleukin-2/Montanide ISA-51/Telomerase: 540-548 Peptide Vaccine [NCIt concept]
- Sargramostim/Telomerase: 540-548 Peptide Vaccine [NCIt concept]

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