Preferred Label : Integrator Complex Subunit 6;
NCIt synonyms : RNA Helicase HDB/DICE1; EGF Repeat Transmembrane Protein; DDX26; DEAD/H Box Protein 26; Protein DDX26; DBI-1; Int6; DEAD/H BOX 26; DICE1; Protein Deleted In Cancer 1; RNA Helicase HDB; DDX26 Protein; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 26; DEAD-H Box Protein-26; INTS6;
NCIt definition : Integrator complex subunit 6 (887 aa, 100 kDa) is encoded by the human INTS6 gene.
This protein is involved in the synthesis of small nuclear RNA.;
NCIt note : Encoded by human DDX26 Gene (DEAD Family), the highly conserved candidate tumor suppressor
1687-amino acid 188.5-kD DEAD/H Box Protein 26 contains a vWF type A domain. With
a likely important cellular function, DDX26 is expressed in a variety of fetal and
adult tissues. DEAD box proteins, characterized by a conserved Asp-Glu-Ala-Asp (DEAD)
motif, are putative RNA helicases that alter RNA secondary structure and influence
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome
assembly. Based on distribution, some family members may be involved in embryogenesis,
spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM,
and NCI);
Origin ID : C26357;
UMLS CUI : C0909050;
OMIM relation
- Semantic type(s)
- gene_encodes_gene_product
- gene_product_has_organism_source
- gene_product_plays_role_in_biological_process
