Leucine-Rich Glioma-Inactivated Protein 1

Preferred Label : Leucine-Rich Glioma-Inactivated Protein 1;

NCIt synonyms : LGI1; LGI1 Protein; Epitempin 1; Leucine-Rich Glioma-Inactivated Protein; BA512J3.1; Leucine-Rich Glioma-Inactivated 1;

NCIt definition : Leucine-rich glioma-inactivated protein 1 (557 aa, 64 kDa) is encoded by the human LGI1 gene. This protein plays a role in the regulation of voltage-gated potassium channel assembly and activity.;

Alternative definition : CDISC: An antigen encoded by the LGI1 gene and is involved in the regulation of voltage-gated potassium channel assembly and activity. It can be considered as an autoantigen and is commonly associated with autoimmune encephalitis.;

Détails

Origin ID

C26353;

UMLS CUI

C0761756;

OMIM relation
- Leucine-rich gene, glioma-inactivated, 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LGI1 protein, human [MeSH Supplementary Concept]
- LGI1 protein, human [MeSH concept]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- LGI1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
gene_product_malfunction_associated_with_disease
- Congenital Epilepsy [NCIt concept]
- Malignant Glioma [NCIt concept]
gene_product_plays_role_in_biological_process
- Inhibition of Cancer Cell Growth [NCIt concept]
- Ion Transport Process [NCIt concept]
- Neuronal Transmission [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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