NCIt definition : A humanized monoclonal antibody against the fusion protein (F protein) of human respiratory
syncytial virus (RSV), with prophylactic application in respiratory syncytial virus
infections. RSV F protein, a small envelop glycoprotein, is not only required for
cytopathic syncytia resulting from cell-to-cell fusion, but is also necessary for
viral spreading and evading neutralizing antibody. Palivizumab neutralizes and inhibits
fusion activity of RSV, thereby preventing syncytia formation. Administration of this
antibody does not interfere with other immunizations.;