COP9 Signalosome Complex Subunit 1

Preferred Label : COP9 Signalosome Complex Subunit 1;

NCIt synonyms : GPS1 Protein; G Protein Pathway Suppressor 1; GPS1; MFH Protein; Arabidopsis FUS6/COP11 Homolog; SGN1; G Protein Pathway Suppressor-1 Protein; GPS-1; JAB1-Containing Signalosome Subunit 1; Signalosome Subunit 1; G Protein Pathway Suppressor 1 Protein; COP9 Signalosome Subunit 1;

NCIt definition : COP9 signalosome complex subunit 1 (491 aa, 56 kDa) is encoded by the human GPS1 gene. This protein plays a role in the regulation of the ubiquitin (Ubl) conjugation pathway and the suppression of G-protein and mitogen-activated protein kinase-mediated signal transduction.;

Details

Origin ID

C26246;

UMLS CUI

C0753882;

OMIM relation
- G protein pathway suppressor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GPS1 protein, human [MeSH concept]
- GPS1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- GPS1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_plays_role_in_biological_process
- Deubiquitination [NCIt concept]
- Signal Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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