Endothelin-2 - CISMeF

Preferred Label : Endothelin-2;

NCIt synonyms : Endothelin 2; EDN2; ET-2; Preproendothelin-2; PPET2; Preproendothelin 2;

NCIt definition : Endothelin-2 (178 aa, 20 kDa) is encoded by the human EDN2 gene. This protein plays a role in vasoconstriction.;

NCIt note : Endothelin-2 is proteolytically processed to form a 21 amino acid peptide also called endothelin-2. (UniProt);

Détails

Origin ID

C26151;

UMLS CUI

C4316928;

Automatic exact mappings (from CISMeF team)
- Endothelin 2 [OMIM gene]
- big endothelin 2 [MeSH concept]
- big endothelin 2 [MeSH Supplementary Concept]
- endothelin 2 [HGNC gene]
- preproendothelin 2 [MeSH concept]
- preproendothelin 2 [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Endothelin-2 [MeSH Descriptor]
- Endothelin-2 [MeSH concept]
OMIM relation
- Endothelin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- EDN2 Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_expressed_in_tissue
- Endothelium [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Endothelin Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
- Muscle Contraction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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