Preferred Label : Yttrium Y 90 Daclizumab;
NCIt synonyms : Y90 Daclizumab; Y90 MOAB Anti-Tac;
NCIt definition : A synthetic radioimmunoconjugate comprised of a humanized anti-interleukin-2 (IL-2)
antibody linked to the radioisotope Yttrium 90 with potential antineoplastic activity.
Daclizumab binds with high affinity to the Tac (also called CD25) subunit of the IL-2
receptor complex and inhibits the binding of IL-2, thereby blocking the IL-2-mediated
activation of lymphocytes. As Yttrium Y 90 daclizumab, daclizumab delivers radiation
specifically to lymphocytes that express the IL-2 receptor. (NCI04);
Origin ID : C2600;
UMLS CUI : C0935688;
Semantic type(s)
- concept_is_in_subset
- has_target
