Preferred Label : Organic Cation Transporter-Like 2 Protein;
Obsolete resource : true;
NCIt synonyms : Imprinted Polyspecific Membrane Transporter 1; Tumor-Suppressing STF 5; Solute Carrier Family 22, Organic Cation Transporter, Member 1-Like;
NCIt definition : Encoded by human SLC22A1L Gene (Polyspecific Transporter/Multidrug Resistance Family),
424-amino acid Organic Cation Transporter-Like 2 Protein has ten transmembrane segments.
Highest expression occurs in liver, heart, and kidney. The SLC22A1L organic cation
transporter protein is localized on the apical surface of renal proximal tubules and
appears to confer resistance/transport activity to chloroquine and quinidine-related
compounds. Renal epithelial cell apical and basolateral polyspecific organic-cation
transporters mediate excretion of endogenous and exogenous compounds. (from OMIM and
NCI);
Concept status : Retired_Concept;
Origin ID : C25861;
OMIM relation
- Semantic type(s)
