NCIt related terms : In 111 Zevalin; In 111 ibritumomab tiuxetan; indium In 111 ibritumomab tiuxetan;
NCIt definition : A targeted radioimmunoconjugate composed of a murine monoclonal anti-CD20 antibody
(ibritumomab) linked by a chelator (tiuxetan) to the imaging radioisotope indium-111.
This radioimmunoconjugate binds to CD20-positive cells, permitting radioimmuno-localization
of CD20-positive cell biodistribution.;
Alternative definition : NCI-GLOSS: A radiolabeled monoclonal antibody that is used to detect certain types
of B-cell non-Hodgkin lymphoma and is being studied in the detection of other types
of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope
indium 111. It binds to the protein called CD20, which is found on B cells. A machine
is used to detect which cells in the body have bound the antibody. In 111 ibritumomab
tiuxetan is a type of radiopharmaceutical.;
UNII : S9U4ZR2W8V;
Molecule name : IDEC In2B8; IDEC-In2B8;
Chemical formula : C23H27N5O10S.2H.In;
NSC code : 950023;
Codes from synonyms : CDR0000046194; CDR0000579671; CDR0000579673;
Semantic type(s)