Anthramycin - CISMeF

Preferred Label : Anthramycin;

NCIt synonyms : 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1h-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-2-propenamide;

NCIt definition : A pyrrolo(1,4)benzodiazepine antineoplastic antibiotic isolated from the bacterium Streptomyces refuineus var. thermotolerans. Anthramycin binds covalently to guanine in the minor groove of DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04);

UNII : 0WZD9Y66WN;

InChIKey : VGQOVCHZGQWAOI-YQRHFANHSA-N;

CAS number : 4803-27-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 4803-27-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C16H17N3O4;

Details

Origin ID

C252;

UMLS CUI

C0003167;

Automatic exact mappings (from CISMeF team)
- Anthramycin [ICHI extension code]
Currated CISMeF NLP mapping
- Antramycin [ICD-11 Extension code]
- anthramycin [MeSH Descriptor]
- anthramycin [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Antramycin [ICD-11 Extension code]
- anthramycin [MeSH concept]
- anthramycin [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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