anthramycin - CISMeF

Preferred Label : anthramycin;

MeSH definition : A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.;

MeSH synonym : antramycin;

MeSH hyponym : anthramycin, (11a alpha)-Isomer;

MeSH CAS label : 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-;

MeSH Related Number : anthramycin, (11a alpha)-Isomer; 35599-87-2 ((11a alpha)-isomer); 4803-27-4 (Anthramycin);

Registry Number MeSH : 4803-27-4;

Related CAS MeSH : 35599-87-2 (Anthramycin, (11a alpha)-Isomer);

Wikipedia link : https://en.wikipedia.org/wiki/Anthramycin;

Is substance : O;

UNII : 0WZD9Y66WN;

InChIKey : VGQOVCHZGQWAOI-YQRHFANHSA-N;

Details

Origin ID

D000876;

UMLS CUI

C0003167;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Anthramycin [ICHI extension code]
- Anthramycin [NCIt concept]
- Antramycin [ICD-11 Extension code]
- Antramycin [SMS substance]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
Record concept(s)
- anthramycin [MeSH concept]
- anthramycin, (11a alpha)-Isomer [MeSH concept]
Related MeSH Supplementary Concept(s)
- (11R,11aS)-2-(N,N-dimethyl)acrylamide-1,10,11,11a-tetrahydro-11-methoxy-7,8-methylenedioxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one [MeSH Supplementary Concept]
- 1,11a-didehydroanhydroanthramycin [MeSH Supplementary Concept]
- abbeymycin [MeSH Supplementary Concept]
- anthramycin 11-methyl ether [MeSH Supplementary Concept]
- anthramycin-DNA [MeSH Supplementary Concept]
- mazethramycin [MeSH Supplementary Concept]
- porothramycin A [MeSH Supplementary Concept]
- porothramycin B [MeSH Supplementary Concept]
- usabamycin A [MeSH Supplementary Concept]
- usabamycin B [MeSH Supplementary Concept]
- usabamycin C [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Anthramycin [NCIt concept]
- Antramycin [ICD-11 Extension code]

Keyword's position in hierarchy(ies) :

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