Monoclonal Antibody HeFi-1

Preferred Label : Monoclonal Antibody HeFi-1;

NCIt synonyms : HeFi-1; MoAb HeFi-1;

NCIt definition : A murine monoclonal antibody with potential antineoplastic activity. Monoclonal antibody HeFi-1 binds to CD30, a cell surface antigen found on mitogen-activated B-cells and T-cells, and Reed-Sternberg cells. Monoclonal antibody HeFi-1 has been shown to arrest tumor growth and prevent metastasis in animal models. (NCI04);

NSC code : 603573;

Details

Origin ID

C2505;

UMLS CUI

C0796480;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_abnormal_cell
- Reed-Sternberg Cell [NCIt concept]
chemical_or_drug_affects_cell_type_or_tissue
- B-Lymphocyte [NCIt concept]
- T-Lymphocyte [NCIt concept]
chemical_or_drug_affects_gene_product
- Tumor Necrosis Factor Receptor Superfamily Member 8 [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]
- Metastasis Suppression [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Tumor Necrosis Factor Receptor Superfamily Member 8 [NCIt concept]

Keyword's position in hierarchy(ies) :

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