" /> Etanercept - CISMeF





Preferred Label : Etanercept;

NCIt synonyms : Tumor Necrosis Factor Receptor IgG Chimera; TNFR:Fc;

NCIt definition : A recombinant soluble dimeric fusion protein consisting of the extracellular ligand-binding region of recombinant human tumor necrosis factor (rhTNF) receptor attached to the constant (Fc) region of human immunoglobulin G (FcIgG). The receptor moiety of etanercept binds to circulating TNF (2 molecules of TNF per receptor) and inhibits its attachment to endogenous TNF cell surface receptors, thereby rendering TNF inactive and inhibiting TNF-mediated mechanisms of inflammation. (NCI04);

Alternative definition : NCI-GLOSS: A drug that is commonly used to treat arthritis. It is also being studied in the treatment of cancer, and as a treatment for loss of appetite and weight loss in cancer patients. It belongs to the family of drugs called tumor necrosis factor (TNF) antagonists.;

UNII : OP401G7OJC;

CAS number : 185243-69-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 185243-69-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Enbrel;

Codes from synonyms : CDR0000285635;

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15/05/2024


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