NCIt definition : A cancer vaccine consisting of GM2 ganglioside, a melanoma-specific antigen, conjugated
with the immunostimulant keyhole limpet hemocyanin. Vaccination with GM2-KLH vaccine
may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response
against GM2 ganglioside-expressing melanoma cells, resulting in tumor growth inhibition.
(NCI04);
Alternative definition : NCI-GLOSS: A substance used to stimulate the production of antibodies that fight certain
cancer cells.;
Semantic type(s)