Thyroglobulin - CISMeF

Preferred Label : Thyroglobulin;

NCIt synonyms : TG;

NCIt related terms : Thyroid Thyroglobulin;

NCIt definition : Thyroglobulin (2768 aa, 305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis.;

Alternative definition : NCI-GLOSS: The form that thyroid hormone takes when stored in the cells of the thyroid. If the thyroid has been removed, thyroglobulin should not show up on a blood test. Doctors measure thyroglobulin level in blood to detect thyroid cancer cells that remain in the body after treatment.; CDISC: An antigen encoded by the TG gene that regulates thyroid hormone synthesis. It can be considered as an autoantigen and is commonly associated with autoimmune thyroid diseases.;

NCIt note : Thyroglobulin is the precursor for both the free and iodinated forms of thyroxine (T4) and triiodothyronine (T3).;

Codes from synonyms : CDR0000044556;

Details

Origin ID

C2304;

UMLS CUI

C5196781;

Currated CISMeF NLP mapping
- Thyroglobulin [ICD-11 Extension code]
- Thyroglobulin [LOINC component]
- Thyroglobulin [MedDRA Preferred Term]
- thyroglobulin [MeSH Descriptor]
- thyroglobulin [MeSH concept]
- thyroglobulin [SNOMED Notion]
- thyroglobulin [ORDO Gene]
- thyroglobulins [Substance BNPC]
False automatic mappings
- Product containing tioguanine (medicinal product) [SNOMED CT concept]
- Thyroglobulin (substance) [SNOMED CT concept]
OMIM relation
- Thyroglobulin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing thyroglobulin (medicinal product) [SNOMED CT concept]
- TG protein, human [MeSH Supplementary Concept]
- Thyroglobulin [LOINC component]
- Thyroglobulin (substance) [SNOMED CT concept]
- thyroglobulin [MeSH Descriptor]
- thyroglobulin [MeSH concept]
- thyroglobulin [SNOMED Notion]
- thyroglobulin preparation [SNOMED Notion]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- Peptide Hormone Gene [NCIt concept]
- TG Gene [NCIt concept]
gene_product_expressed_in_tissue
- Thyroid Gland [NCIt concept]
gene_product_is_element_in_pathway
- Autoimmune Thyroid Disease Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]
is_target
- Anti-thyroglobulin mTCR-transduced Autologous Peripheral Blood Lymphocytes [NCIt concept]

Keyword's position in hierarchy(ies) :

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