Preferred Label : Immunohistochemistry Staining Method;
NCIt synonyms : Cell/Tissue, Immunohistochemistry; IHC;
NCIt related terms : immunohistochemistry; Immunohistochemistry (IHC);
NCIt definition : Immunohistochemical staining techniques allow for the visualization of antigens via
the sequential application of a specific antibody to the antigen (primary antibody),
a secondary antibody to the primary antibody and an enzyme complex with a chromogenic
substrate. The enzymatic activation of the chromogen results in a visible reaction
product at the antigen site. The specimen may then be counterstained and coverslipped.
Results are interpreted using a light microscope and aid in the differential diagnosis
of pathophysiological processes, which may or may not be associated with a particular
antigen.;
Alternative definition : NCI-GLOSS: A technique used to identify specific molecules in different kinds of tissue.
The tissue is treated with antibodies that bind the specific molecule. These are made
visible under a microscope by using a color reaction, a radioisotope, colloidal gold,
or a fluorescent dye. Immunohistochemistry is used to help diagnose diseases, such
as cancer, and to detect the presence of microorganisms. It is also used in basic
research to understand how cells grow and differentiate (become more specialized).;
Codes from synonyms : CDR0000653117;
Origin ID : C23020;
UMLS CUI : C0021044;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
https://kce.fgov.be/fr/publications/tous-les-rapports/utilisation-des-marquages-immunohistochimiques-et-de-la-microscopie-electronique-en-belgique
2024
Belgium
technical report
french abstract
Electron Microscopy
belgium
Use
microscopy, electron
Immunohistochemistry Staining Method
Belgium
immunohistochemistry
electron microscopic study, nos
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