Amikacin Sulfate

Preferred Label : Amikacin Sulfate;

NCIt synonyms : Amikacin;

NCIt definition : The sulfate salt of amikacin, a broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically in contact with 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.;

UNII : N6M33094FD;

InChIKey : FXKSEJFHKVNEFI-GCZBSULCSA-N;

CAS number : 39831-55-5;

Drug name : Amikin;

Chemical formula : C22H43N5O13.2H2O4S;

NSC code : 177001;

ChEBI ID : CHEBI:2638;

Details

Origin ID

C230;

UMLS CUI

C0002501;

Automatic exact mappings (from CISMeF team)
- Amikacin [LOINC component]
- Amikacin [ICHI extension code]
- amikacin [MeSH Descriptor]
- amikacin [MeSH concept]
- amikacin [Substance BNPC]
- amikacin [ATC Code]
- amikacin [SNOMED Notion]
- amikacin [ATC Code]
- amikacin [ATC Code]
- amikacin [EMDN type]
- amikacin [medical devices type]
See also inter- (CISMeF)
- Product containing amikacin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
Validated automatic mappings to NTBT
- Amikacin [ICD-11 Extension code]
- Amikacin [SMS substance]
- Amikacin (substance) [SNOMED CT concept]
- amikacin [MeSH Descriptor]
- amikacin [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Amikacin [NCIt concept]
is_component_of_chemotherapy_regimen
- Amikacin/Ceftazidime [NCIt concept]
- Amikacin/Ceftriaxone [NCIt concept]
is_salt_form_of
- Amikacin [NCIt concept]

Keyword's position in hierarchy(ies) :

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