Glucagon - CISMeF

Preferred Label : Glucagon;

NCIt synonyms : Hyperglycemic Glycogenolytic Factor; HG-Factor; HG Factor; GCG; Hyperglycemic-Glycogenolytic Factor;

NCIt definition : Glucagon (29 aa, 3 kDa) is encoded by the human GCG gene. This protein plays a role in the regulation of blood sugar levels through the stimulation of hepatic glycogenolysis and gluconeogenesis.;

Alternative definition : NCI-GLOSS: A hormone produced by the pancreas that increases the level of glucose (sugar) in the blood.;

NCIt note : Glucagon is comprised of amino acids 53-81 of the full length proglucagon precursor protein. (UniProt);

Codes from synonyms : CDR0000270860;

Details

Origin ID

C2268;

UMLS CUI

C0772088;

Automatic exact mappings (from CISMeF team)
- GCG [EDAM format]
- Glucagon [OMIM gene]
- Glucagon [LOINC Challenge]
- Glucagon low [MedDRA LLT]
- glucagon [HGNC gene]
- glucagon [EMDN type]
- glucagon [medical devices type]
- pre dose glucagon [LOINC Challenge]
False automatic mappings
- glucagon (1-17) [MeSH concept]
- glucagon (1-17) [MeSH Supplementary Concept]
- glucagon (1-21) [MeSH concept]
- glucagon (1-21) [MeSH Supplementary Concept]
- glucagon (1-6) [MeSH concept]
- glucagon (1-6) [MeSH Supplementary Concept]
- glucagon (19-29) [MeSH concept]
- glucagon (19-29) [MeSH Supplementary Concept]
OMIM relation
- Glucagon [OMIM gene]
See also inter- (CISMeF)
- Glucagon [MedDRA LLT]
- Product containing glucagon (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GCG Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_expressed_in_tissue
- Islet of Langerhans [NCIt concept]
gene_product_has_associated_anatomy
- Alpha Cell [NCIt concept]
gene_product_is_element_in_pathway
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Gluconeogenic Process [NCIt concept]
- Glycolysis Inhibition [NCIt concept]
- Intercellular Communication Process [NCIt concept]
has_salt_form
- Glucagon Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Glucagon Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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