Prasterone - CISMeF

Preferred Label : Prasterone;

NCIt synonyms : Therapeutic Dehydroepiandrosterone; 3beta-Hydroxyandrost-5-en-17-one; 17-Hormoforin; DHEA; 5,6-Dehydroisoandrosterone;

NCIt related terms : Dehydroepiandrosterone; Dehydroisoandrosterone;

NCIt definition : A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04);

Alternative definition : NCI-GLOSS: A substance being studied in the prevention of cancer. It is a type of steroid.;

UNII : 459AG36T1B;

InChIKey : FMGSKLZLMKYGDP-USOAJAOKSA-N;

CAS number : 53-43-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 53-43-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Diandron; Fidelin;

Molecule name : GL701;

Chemical formula : C19H28O2;

NSC code : 9896;

ChEBI ID : CHEBI:28689;

Codes from synonyms : 00051; NSC0009896; CDR0000045471; CDR0000044986;

Details

Origin ID

C2265;

UMLS CUI

C0011185;

Automatic exact mappings (from CISMeF team)
- prasterone [ATC Code]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dehydroepiandrosterone [LOINC component]
- Dehydroepiandrosterone (substance) [SNOMED CT concept]
- Prasterone [ICD-11 Extension code]
- Product containing dehydroepiandrosterone (medicinal product) [SNOMED CT concept]
- androstenolone [SNOMED Notion]
- dehydroepiandrosterone [MeSH concept]
- dehydroepiandrosterone [MeSH Descriptor]
- dehydroepiandrosterone [SNOMED Notion]
- prasterone [ATC Code]
- prasterone [Substance BNPC]
- prasterone [ATC Code]
Validated automatic mappings to BTNT
- prasterone [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_salt_form
- Sodium Prasterone Sulfate Dihydrate [NCIt concept]
is_free_acid_or_base_form_of
- Sodium Prasterone Sulfate Dihydrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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