NCIt related terms : Dehydroepiandrosterone; Dehydroisoandrosterone;
NCIt definition : A synthetic form of dehydroepiandrosterone with potential chemopreventive activity.
Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion
of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously
administered DHEA have not been fully illuminated, they may result in both direct
and indirect physiologic effects. Direct effects include GABA-a receptor complex and
NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and
antiglucocorticoid activities. (NCI04);
Alternative definition : NCI-GLOSS: A substance being studied in the prevention of cancer. It is a type of
steroid.;
UNII : 459AG36T1B;
InChIKey : FMGSKLZLMKYGDP-USOAJAOKSA-N;
CAS number : 53-43-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 53-43-0
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G-SRS /a ;
Drug name : Diandron; Fidelin;
Molecule name : GL701;
Chemical formula : C19H28O2;
NSC code : 9896;
ChEBI ID : CHEBI:28689;
Codes from synonyms : 00051; NSC0009896; CDR0000045471; CDR0000044986;