" /> Tariquidar - CISMeF





Preferred Label : Tariquidar;

NCIt related terms : XR9576;

NCIt definition : An anthranilamide derivative with multidrug resistance properties. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It may help tumor cells respond again to drugs they have become resistant (unable to respond) to. Tariquidar is a type of multidrug resistance inhibitor and a type of P-glycoprotein antagonist.;

UNII : J58862DTVD;

InChIKey : LGGHDPFKSSRQNS-UHFFFAOYSA-N;

CAS number : 206873-63-4;

Molecule name : XR9576;

Chemical formula : C38H38N4O6;

Codes from synonyms : CDR0000301627; CDR0000044895;

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Keyword's position in hierarchy(ies) : arborescence

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24/05/2025


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