Liposomal Daunorubicin Citrate

Preferred Label : Liposomal Daunorubicin Citrate;

NCIt synonyms : Daunorubicin Liposomal; Liposomal Daunorubicin; Daunorubicin Citrate Liposome Injection;

NCIt related terms : Daunorubicin (Liposomal);

NCIt definition : A liposome-encapsulated form of the citrate salt of the anthracycline antineoplastic antibiotic daunorubicin. Daunorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Liposomal delivery of doxorubicin citrate improves drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic drug effects.;

Drug name : DaunoXome;

NSC code : 697732;

Codes from synonyms : 144;

Details

Origin ID

C2213;

UMLS CUI

C0724567;

Currated CISMeF NLP mapping
- Daunorubicin citrate liposome (substance) [SNOMED CT concept]
See also inter- (CISMeF)
- Daunorubicin liposomal (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Daunorubicin citrate liposome (substance) [SNOMED CT concept]
Validated automatic mappings to NTBT
- Daunorubicin liposome (substance) [SNOMED CT concept]
concept_is_in_subset
- AML Authorized Value Terminology [NCIt concept]
- AML Total Dose Table [NCIt concept]
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Topoisomerase II [NCIt concept]
is_component_of_chemotherapy_regimen
- Cytarabine/Daunorubicin Liposomal [NCIt concept]
- Daunorubicin Liposomal/SU5416 [NCIt concept]

Keyword's position in hierarchy(ies) :

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