Preferred Label : Androgen Receptor Degrader CC1083610;
NCIt synonyms : AR Degrader CC1083610;
NCIt definition : An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic
activity. Upon oral administration, AR degrader CC1083610 causes degradation of AR,
prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing
tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant
prostate cancer (CRPC). CC1083610 is the R,S diastereomer of its R,R diastereomer
CC1083611 (BMS-986409), and gridegalutamide is a 50:50 mixture of CC1083610 and CC1083611.;
Molecule name : BMS 986410; CC 1083610; CC-1083610; BMS-986410;
Origin ID : C217660;
concept_is_in_subset
- has_target
