Preferred Label : Epitinib;
NCIt synonyms : HMPL813 Base Form; HMPL 813 Base Form; HMPL-813 Base Form; 4-Ethyl-N-(4-((3-ethynylphenyl)amino)-7-methoxy-6-quinazolinyl)-1-piperazinecarboxamide;
NCIt definition : An orally available epidermal growth factor receptor (EGFR) inhibitor, with potential
antineoplastic activity. Upon administration, epitinib inhibits the activity of EGFR,
thereby preventing EGFR-mediated signaling. This may lead to induction of cell death
and inhibition of tumor growth in EGFR-overexpressing tumor cells. EGFR is a receptor
tyrosine kinase (RTK) that is overexpressed in certain tumor types and plays a key
role in tumor cell proliferation and vascularization.;
UNII : WZ97ZE4UUG;
CAS number : 1203902-67-3;
Origin ID : C217160;
concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
