Preferred Label : Epitinib Succinate;
NCIt definition : The succinate salt form of epitinib, an orally available epidermal growth factor receptor
(EGFR) inhibitor, with potential antineoplastic activity. Upon administration, epitinib
inhibits the activity of EGFR, thereby preventing EGFR-mediated signaling. This may
lead to induction of cell death and inhibition of tumor growth in EGFR-overexpressing
tumor cells. EGFR is a receptor tyrosine kinase (RTK) that is overexpressed in certain
tumor types and plays a key role in tumor cell proliferation and vascularization.;
UNII : 2138WW3F3R;
CAS number : 2252334-12-4;
Molecule name : HMPL 813; HMPL-813;
NCI Metathesaurus CUI : CL554354;
Origin ID : C153095;
UMLS CUI : C4727018;
Semantic type(s)
- concept_is_in_subset
