Autologous Anti-CD83 CAR T-cells

Preferred Label : Autologous Anti-CD83 CAR T-cells;

NCIt synonyms : Autologous Anti-CD83 CAR T Cells; Autologous Anti-CD83 CAR-T Cells;

NCIt definition : A preparation of autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD83, with potential antineoplastic activity. Upon administration, autologous anti-CD83 CAR T-cells recognize and kill CD83-expressing tumor cells. CD83 is expressed on acute myeloid leukemia (AML) blasts.;

Détails

Origin ID

C214495;

chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- CD83 Antigen [NCIt concept]

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